ELRST LVTELVATIONAL STAhTDARD FOR QUANTfTATION OF ANTI-HPA-la
نویسنده
چکیده
This report describes the production and characterisation of a freeze-dried preparation of pooled human plasma, containing IgG antibodies against the human platelet antigen l a (HPA-la). Plasma samples containing potent anti-HPA-la were pooled and freeze dried in 1 mL ampoules. In addition, three individual plasma samples were selected which had varying levels of antiHPA-la activity. The anti-HPA-la activity of these three samples was determined with a variety of quantitative assays using the proposed standard as a reference. An international collaborative study, which was part of the 2004 ISBT Platelet h u n o l o g y Workshop, involved 39 laboratories in 24 countries and showed that the anti-HPA-la activity in three test samples could
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